Side effects of testosterone enanthate include symptoms of masculinization like acne , increased hair growth , voice changes , and increased sexual desire .  The drug is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT).   It has strong androgenic effects and moderate anabolic effects, which make it useful for producing masculinization and suitable for androgen replacement therapy .  Testosterone enanthate is a testosterone ester and a long-lasting prodrug of testosterone in the body.    Because of this, it is considered to be a natural and bioidentical form of testosterone. 
When it comes to steroids, undoubtedly the side effects that scare people the most are those related to estrogen and its side effects. This is very common when you consider the fact that as a man, the primary reason you have masculine features is due to higher levels of testosterone in comparison to estrogen. For women, the inverse is true. This is very important to understand because whenever you dose with an exogenous compound, you’re going to throw your hormone levels out of whack. This means that whenever you do engage in using one of these compounds, you have to understand that whenever you introduce higher levels of androgenic (testosterone producing compounds) compounds, these are going to result in feedback levels of estrogen in response. This is very important to keep in mind because otherwise, you will be unable to stave off the bad effects that you would otherwise experience from the compound.
Drug abuse is intentional non-therapeutic use of a drug, even once, for its rewarding psychological and physiological effects. Abuse and misuse of Testosterone are seen in male and female adults and adolescents. Testosterone, often in combination with other anabolic androgenic steroids (AAS), and not obtained by prescription through a pharmacy, may be abused by athletes and bodybuilders. There have been reports of misuse by men taking higher doses of legally obtained Testosterone than prescribed and continuing Testosterone despite adverse events or against medical advice.