Stanozolol appears to offer less hepatic stress than an equivalent dose of Dianabol (methandrostenolone). Studies giving 12mg of stanozolol per day for 27 weeks failed to demonstrate clinically-significant changes in markers of liver function, including serum aspartate amino-transferase, alanine amino-transferase, gamma-glutamyltransferase, bilirubin, and alkaline phosphatase. 621 Relative hepatotoxicity increases as the dosage escalates, so hepatic dysfunction should still be a concern. In rare instances, high doses (alone or in combination with other steroids) have been implicated in cases of serious life-threatening hepatotoxicity in bodybuilders. Injectable stanozolol has also been implicated in severe hepatotoxicity in an otherwise healthy bodybuilder, 622 and should not be used as an alternative medication when liver toxicity precludes oral stanozolol use.
There are many side effects associated with Winstrol that can occur in both male and female. In women, there are menstrual irregularities as well as clitoral enlargement. In rare cases, Cholestatic jaundice and hepatic necrosis and even death. Men often experience increased erections and even Phallic enlargement. An increase or decrease in libido occurs in both men and women. Other side effects occur with the central nervous system, breast, hair, skin, skeletal, edema, and the endocrine system. One of the main side effects is liver damage.