Max Azria , fashion designer, 69; Omar al-Bashir , president of Sudan, 74; Mary Beard , professor of classics, University of Cambridge, and classics editor of the TLS , 63; Lord (Nicholas) Bourne of Aberystwyth , minister for Wales and minister for faith, 66; Alison Bevan , director, Royal West of England Academy, 53; Sir Tony Brenton , diplomat, UK ambassador to Russia (2004-08), 68; Jon Callard , rugby union player, Bath (1989-99) and England (1993-95), 52; Lord (Anthony) Colwyn , dental surgeon and bandleader, 76; Gia Coppola , film director, Palo Alto (2013), 31; Prof Sir Martin Evans , biologist, Nobel prizewinner (2007), the first scientist to identify embryonic stem cells, 77; Morgan Fisher , musician, Mott the Hoople, 68; John Fuller , poet and novelist, Flying to Nowhere (1983), You’re Having Me On (2014), and expert on WH Auden, 81; Adrian Hall , actor, Chitty Chitty Bang Bang (1968), principal, Academy of Live and Recorded Arts, 59; Abdul Hamid , president of Bangladesh, 74; Jacky Ickx , Belgian racing driver, six-time winner of the Le Mans 24-hour race, 73; Bill Jacklin , painter, 75; Stephen Kinnock , Labour MP for Aberavon, 48; Christine Lagarde , managing director, International Monetary Fund, 62; Frank Langella , actor, Frost/Nixon (2008), Robot & Frank (2012), 80; Paul Lawrie , golfer, winner of the Open (1999), 49; Michael Lynton , chairman, Snap, the Snapchat mobile app, chairman and chief executive, Sony Pictures Entertainment (2004-17), 58; Fuad Masum , president of Iraq, 80; Jimi Mistry , actor, Blood Diamond (2006), Coronation Street (2013-15), 45; Prof Sir Anton Muscatelli , economist, principal and vice-chancellor, University of Glasgow, 56; Alassane Ouattara , president of Ivory Coast, 76; Jonah Peretti , internet entrepreneur, co-founder of BuzzFeed and The Huffington Post, 44; Fiona Phillips , TV presenter, 57; Joseph Saddler (Grandmaster Flash), hip-hop artist, 60; Sharon Small , actress, About a Boy (2002), Mistresses (2008-10), 51; Georgina von Etzdorf , textile and tie designer, 63; Jack Wilshere , footballer, Arsenal and England, 26.
HAS-BLED is a risk score designed to predict the one year risk for major bleeding in AF patients and may be used to aid in clinical decision making regarding anticoagulation therapy. HAS-BLED is an acronym for the bleeding risk factors that are assessed: Hypertension (uncontrolled, > 160 mm Hg systolic), Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile INR, Elderly (age >65 years), and Drugs/alcohol concomitantly (antiplatelet agents, non-steroidal anti-inflammatory drugs). A high HAS-BLED score is associated with a high risk of hemorrhage. When used in conjunction with a stroke risk score, HAS-BLED may be able to help one weigh the stroke risk and bleeding risk to determine the best course of action for anticoagulation therapy. It is important to note however, that CHADS2 and CHADS2-VASc stroke risk scores contain some of the same risk factors as HAS-BLED. The results of the HAS-BLED score should be interpreted with this in mind.
like a river, fashion will break free with overwhelming fluidity becoming the principle of design for the near future. the fluency of the currents and waves and rapids and rivulets is reflected in the fluidity of folds and drapes and smocks and gathers, while froth and foam are rendered with fine pleating, layering and perforation. cascading waterfalls of frills and ruffles will give majestic form to romanticism. breaking waves of fine foamy jerseys will be layered to shield from a sudden summer breeze. the wilder currents of the ocean will stand for conceptual asymmetrical shapes while the stillness of the lake will ripple softly with crêpe and undulating yarns, reflective and minimal in a profound and deep dark blue.